Registered Nurse Salary in St. Louis, MO
Average annual salary for registered nurses. Updated March 2026 with data from BLS, U.S. Census Bureau, and industry surveys.
Average Annual Salary
$47.850 – $82.650
-13% vs national average
$47.850$65.250$82.650
LowNational avg: $75.000High
St. Louis vs State & National Average
| Category | St. Louis | Missouri Avg | National Avg |
|---|---|---|---|
| Average salary | $65.250 | $65.738 | $75.000 |
| Low estimate | $47.850 | $49.304 | $56.250 |
| High estimate | $82.650 | $85.459 | $97.500 |
Salary by Experience Level
| Item | Low | High | |
|---|---|---|---|
| Low estimate | $55.000 | $66.000 | |
| Average | $67.500 | $82.500 | |
| High estimate | $76.000 | $95.000 |
Registered Nurse Salary in Nearby Cities
Frequently Asked Questions
How much does registered nurse salary cost in St. Louis?
In St. Louis, MO, registered nurse salary typically costs between $47.850 and $82.650. The average is $65.250, which is 13% below the national average.
Is St. Louis expensive for registered nurse salary?
St. Louis has a cost-of-living index of 87 (100 = national average). Registered Nurse Salary costs are 13% lower than the national average of $75.000.
What factors affect registered nurse salary costs in St. Louis?
Key factors include local labor costs, cost of materials, market competition, Missouri state regulations, and St. Louis's overall cost of living (index: 87/100). Prices can also vary by season and specific requirements.